2023 – The Ley Lab

Publication Year: 2023

An integrated systems-biology approach reveals differences in formate metabolism in the genus Methanothermobacter.

Casini I, McCubbin T, Esquivel-Elizondo S, Luque GG, Evseeva D, Fink C, Beblawy S, Youngblut ND, Aristilde L, Huson DH, Dräger A, Ley RE, Marcellin E, Angenent LT and Molitor B.

iScience.

26:108016.

(2023).

DOI: https://doi.org/10.1016/j.isci.2023.108016

Obesity is the main driver of altered gut microbiome functions in the metabolically unhealthy.

de la Cuesta-Zuluaga J, Huus KE, Youngblut ND, Escobar JS and Ley RE.

Gut Microbes.

15:2246634.

(2023).

DOI: https://doi.org/10.1080/19490976.2023.2246634

The sound of silence.

Clasen S.

Science.

381:37-38.

(2023).

DOI: https://doi.org/10.1126/science.adi6265

Toward microbiome engineering: Expanding the repertoire of genetically tractable members of the human gut microbiome.

Marsh JW, Kirk C and Ley RE.

Annual Review of Microbiology.

77:427-449.

(2023).

DOI: https://doi.org/10.1146/annurev-micro-032421-112304

ResMiCo: Increasing the quality of metagenome-assembled genomes with deep learning.

Mineeva O, Danciu D, Schölkopf B, Ley RE, Rätsch G, Youngblut ND.

PLoS Computational Biology.

19:e1011001.

(2023).

DOI: https://doi.org/10.1371/journal.pcbi.1011001

Psyllium fiber protects against colitis via activation of bile acid sensor FXR.

Bretin A, Zou J, Yeoh BS, Ngo VL, Winer S, Winer DA, Reddivari L, Pellizzon M, Walters WA, Patterson AD, Ley RE, Chassaing B, Vijay-Kumar M and Gewirtz AT.

Cellular and Molecular Gastroenterology and Hepatology.

15:1421-1442.

(2023).

DOI: https://doi.org/10.1016/j.jcmgh.2023.02.007

Longitudinal comparison of the developing gut virome in infants and their mothers.

Walters WA, Granados AC, Ley C, Federman S, Stryke D, Santos Y, Haggerty T, Sotomayor-Gonzalez A, Servellita V, Ley RE, Parsonnet J and Chiu CY.

Cell Host & Microbe.

31:187–198.

(2023).

DOI: https://doi.org/10.1016/j.chom.2023.01.003

Questioning the fetal microbiome illustrates pitfalls of low-biomass microbial studies.

Kennedy KM, de Goffau MC, Perez-Muñoz ME, Arrieta MC, Bäckhed F, Bork P, Braun T, Bushman FD, Dore J, de Vos WM, Earl AM, Eisen JA, Elovitz MA, Ganal-Vonarburg SC, Gänzle MG, Garrett WS, Hall LJ, Hornef MW, Huttenhower C, Konnikova L, Lebeer S, Macpherson AJ, Massey RC, McHardy AC, Koren O, Lawley TD, Ley RE, O'Mahony L, O'Toole PW, Pamer EG, Parkhill J, Raes J, Rattei T, Salonen A, Segal E, Segata N, Shanahan F, Sloboda DM, Smith GCS, Sokol H, Spector TD, Surette MG, Tannock GW, Walker AW, Yassour M and Walter J.

Nature.

613:639-649.

(2023).

DOI: https://doi.org/10.1038/s41586-022-05546-8

Gestational diabetes is driven by microbiota-induced inflammation months before diagnosis.

Pinto Y, Frishman S, Turjeman S, Eshel A, Nuriel-Ohayon M, Shrossel O, Ziv O, Walters W, Parsonnet J, Ley C, Johnson EL, Kumar K, Schweitzer R, Khatib S, Magzal F, Muller E, Tamir S, Tenenbaum-Gavish K, Rautava S, Salminen S, Isolauri E, Yariv O, Peled Y, Poran E, Pardo J, Chen R, Hod M, Borenstein E, Ley RE, Schwartz B, Louzoun Y, Hadar E and Koren O.

Gut.

5:918-928.

(2023).

DOI: http://dx.doi.org/10.1136/gutjnl-2022-328406

Silent recognition of flagellins from human gut commensal bacteria by toll-like receptor 5.

Clasen SJ, Bell MEW, Borbón A, Lee DH, Henseler ZM, de la Cuesta-Zuluaga J, Parys K, Zou J, Wang Y, Altmannova V, Youngblut ND, Weir JR, Gewirtz AT, Belkhadir Y and Ley RE.

Science Immunology.

8:eabq7001.

(2023).

DOI: https://doi.org/10.1126/sciimmunol.abq7001

Contact

Department of Microbiome Science

Max Planck Institute for Biology Tübingen

Max-Planck-Ring 5, 72076 Tübingen, Germany

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