Gut microbiota as an epigenetic regulator: pilot study based on whole-genome methylation analysis. Kumar H, Lund R, Laiho A, Lundelin K, Ley RE, Isolauri E and Salminen S. MBio. 5:e02113-14. (2014). DOI: https://doi.org/10.1128/mbio.02113-14
Linking genetic variation in toll-like receptor 5 genes to the gut microbiome’s potential to cause inflammation. Leifer CA, McConkey C, Li S, Chassaing B, Gewirtz AT and Ley RE. Immunology Letters. 162: 3-9. (2014). DOI: https://doi.org/10.1016/j.imlet.2014.07.017
Intestinal epithelial cell toll-like receptor 5 regulates the intestinal microbiota to prevent low-grade inflammation and metabolic syndrome in mice. Chassaign B, Ley RE and Gewirtz AT. Gastroenterology. 147:1363-1377. (2014). DOI: https://doi.org/10.1053/j.gastro.2014.08.033
Human genetics shape the gut microbiome. Goodrich JK, Waters JL, Poole AC, Sutter JL, Koren O, Blekhman R, Beaumont M, Van Treuren W, Knight R, Bell JT, Spector TD, Clark AG and Ley RE. Cell. 159: 789-799. (2014). DOI: https://doi.org/10.1016/j.cell.2014.09.053
Advancing the microbiome research community. Huttenhower C, Knight R, Brown CT, Caporaso JG, Clemente JC, Gevers D, Franzosa EA, Kelley ST, Knights D, Ley RE, Marhurkar A, Ravel J and White O. Cell. 159: 227-230. (2014). DOI: https://doi.org/10.1016/j.cell.2014.09.022
Conducting a microbiome study. Goodrich JK, Di Renzi SC, Poole AC, Koren O, Walters WA, Caporaso G, Knight R and Ley RE. Cell. 17: 250-262. (2014). DOI: https://doi.org/10.1016/j.cell.2014.06.037
Diet-induced alterations in gut microflora contribute to lethal pulmonary damage in TLR2/TLR4-deficient mice. Ji Y, Sun S, Goodrich JK, Kim H, Poole AC, Duhamel GE, Ley RE and Qi L. Cell Reports. 10: 137-149. (2014). DOI: https://doi.org/10.1016/j.celrep.2014.05.040
Discordance between changes in the microbiota and pathogenicity in a mouse model of spontaneous colotis. Perez-Munoz M, Bergstrom K, Peng V, Schmaltz R, Jimenez-Cardona R, Marsteller N, McGee S, Clavel T, Ley RE, Xia L and Peterson D. Gut Microbes. 5:286-295. (2014). DOI: https://doi.org/10.4161/gmic.28622
Harnessing microbiota to kill a pathogen: the sweet tooth of Clostridium difficile. Ley RE. Nature Medicine. 20:248-249. (2014). DOI: https://doi.org/10.1038/nm.3494
