Wir interessieren uns für die Koevolution von Menschen und deren Mikrobiomen

Mit einem evolutionären Ansatz stellen wir die Frage, wie sich die Gemeinschaften von Mikroorganismen im Darm an das Leben im menschlichen Wirt anpassten.

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Aktuelle Nachrichten

The last issue of Cell Host and Microbe is dedicated to phages and includes our study on viruses in the human gut. This paper shows how we examined...

Curious about your gut microbiome and how you digest lactose? We’re looking for hundreds more mothers to participate at our partnering Institute of...

Leonardo Moreno -a PhD student from our lab- and colleagues have recently published on BioRxiv a research article on the relationship between...

Ausgewählte Veröffentlichungen

Poole A.C., Goodrich J.K., Youngblut N.D., Luque G.G., Ruaud A., Sutter J.L., Waters J.L., Shi Q., El-Hadidi M., Johnson L.M., Bar H.Y., Huson D.H., Booth J.G. and R.E. Ley. Human salivary amylase gene copy number impacts oral and gut microbiomes. Cell Host & Microbe (In Press).

Moreno-Gallego J. L., Chou S. P., Di Rienzi S. C., Goodrich J. K., Spector T., Bell J. T., Youngblut N., Hewson I., Reyes A. and R. E. Ley : Virome diversity correlates with intestinal microbiome diversity in adult monozygotic twins. Cell Host & Microbe 25: 261-272. (2019).

Walters W. A., Jin Z., Youngblut N., Wallace J. G., Sutter J., Zhang W., González-Peña A., Peiffer J., Koren  O., Shi  Q., Rob Knight, Glavina del Rio T., Tringe S. G., Buckler E. S., Dangl J. L., and Ley R. E. Large-scale replicated field study of maize rhizosphere identifies heritable microbes. Proceedings of the National Academy of Sciences USA pii: 201800918 (2018).

Goodrich, J. K. , E. R. Davenport, M. A. Jackson, M. Beaumont, R. Knight, T. D. Spector, J. T. Bell, A. G. Clark, R. E. Ley. Genetic determinants of the gut microbiome assessed in UK Twins. Cell Host & Microbe 19:731-43. (2016).

Goodrich, J. K., E. R. Davenport, J. L. Waters, A. G. Clark and R. E. Ley. Cross-species comparisons of host genetic associations with the microbiome. Science 352: 532-535. (2016).

Goodrich, J. K.,  J. L. Waters, A. C. Poole, J. L. Sutter, O. Koren, R. Blekhman, M. Beaumont, W. Van Treuren, R. Knight, J. T. Bell, T. D. Spector, A. G. Clark and R. E. Ley. Human genetics shape the gut microbiome. Cell 159: 789-799. (2014).