We are interested in the co-evolution of humans with their microbiomes

We take an evolutionary perspective to ask how microbial communities in the gut adapted to life in the human host.

Learn more Publications

Latest News

Yesterday, Jessica Summers, a PhD student from our lab, earned the second place in the Best Oral Presentations of the 2018 Joint PhD Student Symposium...

This afternoon, Albane Ruaud, a PhD student from our lab, has been awarded with the prize to the Best Short Talk of the 2018 Joint PhD Student...

Dr.Victor Schmidt, a postdoc in our lab, is bringing a talk microbiome-mediated lactose tolerance across ethnicities in the International Conference...

Selected Publications

Walters W. A., Jin Z., Youngblut N., Wallace J. G., Sutter J., Zhang W., González-Peña A., Peiffer J., Koren  O., Shi  Q., Rob Knight, Glavina del Rio T., Tringe S. G., Buckler E. S., Dangl J. L., and Ley R. E. Large-scale replicated field study of maize rhizosphere identifies heritable microbes. Proceedings of the National Academy of Sciences USA pii: 201800918 (2018)

Di Rienzi S. C., Jacobson J., Kennedy E. A., Bell M. E., Shi Q., Waters J. L., Lawrence P., Brenna J. T., Britton R. A., Walter J., and Ley R. E. Resilience of small intestinal beneficial bacteria to the toxicity of soybean oil fatty acids. eLife 7:e32581 (2018)

Goodrich, J. K. , E. R. Davenport, M. A. Jackson, M. Beaumont, R. Knight, T. D. Spector, J. T. Bell, A. G. Clark, R. E. Ley. Genetic determinants of the gut microbiome assessed in UK Twins. Cell Host & Microbe 19:731-43. (2016)

Goodrich, J. K., E. R. Davenport, J. L. Waters, A. G. Clark and R. E. Ley. Cross-species comparisons of host genetic associations with the microbiome. Science 352: 532-535. (2016)

Goodrich, J. K.,  J. L. Waters, A. C. Poole, J. L. Sutter, O. Koren, R. Blekhman, M. Beaumont, W. Van Treuren, R. Knight, J. T. Bell, T. D. Spector, A. G. Clark and R. E. Ley. Human genetics shape the gut microbiome. Cell 159: 789-799. (2014)

DiRienzi, S. C., I. Sharon*, K. C. Wrighton, O. Koren, L. A. Hug, B. C. Thomas, J. K. Goodrich, J. T. Bell, T. D. Spector, J. F. Banfielda and R. E. Ley.  The human gut and groundwater harbor non-photosynthetic bacteria belonging to a new candidate phylum sibling to Cyanobacteria. eLife 2:e01102 (2013)

Koren, O., J. K. Goodrich, T. C. Cullender, A. Spor, K. Laitinen, H. Backhed, A. Gonzalez, J. J. Werner, L. T. Angenent, R. Knight, F. Backhed, E. Isolauri, S. Salminen and R. E. Ley. Remodeling of the gut microbiome and metabolic changes during pregnancy. Cell 150: 1-11 (2012).